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Investigation of the mechanisms underlying the effect of oleic acid and docosahexaenoic acid on DNA methylation in Jurkat cells

2019-01-01

Abstract excerpt

There is evidence that olive oil, rich in oleic acid (OA), and fish oil, rich in docosa-hexaenoic acid (DHA), can modify the DNA methylation in human blood cells in vivo. However, the mechanisms underlying such effect are not well understood. To address this, a model to study DNA methylation changes was developed using the in vitro treatment of Jurkat cells with OA or DHA. Analysis showed that 15μM OA or DHA treat...

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Identifiers and source

Literature Corpus work
2ba60e50-cb63-5fb0-845a-4a21c71a3a05
DOI
10.5258/soton/t0013
Open publication

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Investigation of the mechanisms underlying the effect of oleic acid and docosahexaenoic acid on DNA methylation in Jurkat cellsDOI 10.5258/soton/t0013
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