Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Transcription Factor SomA Synchronously Regulates Biofilm Formation and Cell Wall Homeostasis in Aspergillus fumigatus

9 Nov 2020

Abstract excerpt

The cell wall is essential for fungal viability and is absent from human hosts; thus, drugs disrupting cell wall biosynthesis have gained more attention. Caspofungin is a member of a new class of clinically approved echinocandin drugs to treat invasive aspergillosis by blocking β-1,3-glucan synthase, thus damaging the fungal cell wall. Here, we demonstrate that caspofungin and other cell wall stressors can induce...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antifungal resistance and susceptibility
Share to Fungal and yeast genetics research
Share to Polysaccharides and Plant Cell Walls

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33173002
DOI: 10.1128/mbio.02329-20

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Transcription Factor SomA Synchronously Regulates Biofilm Formation and Cell Wall Homeostasis in Aspergillus fumigatusPMID 33173002Read ↗

The histone acetyltransferase GcnE regulates conidiation and biofilm formation in Aspergillus fumigatusSemantic proximity Read ↗

PtaB, a lim-domain binding protein inAspergillus fumigatusregulates biofilm formation and conidiation through distinct pathwaysSemantic proximity Read ↗

Aspergillus fumigatus calcium-responsive transcription factors regulate cell wall architecture promoting stress tolerance, virulence and caspofungin resistance.Semantic proximity Read ↗

Filamentous fungal biofilms: Conserved and unique aspects of extracellular matrix composition, mechanisms of drug resistance and regulatory networks in Aspergillus fumigatusSemantic proximity Read ↗

The Fungal Cell Wall: Structure, Biosynthesis, and FunctionSemantic proximity Read ↗

Adaptive morphological changes link to poor clinical outcomes by conferring echinocandin tolerance in Candida tropicalisSemantic proximity Read ↗

Aspergillus Galactosaminogalactan Mediates Adherence to Host Constituents and Conceals Hyphal β-Glucan from the Immune SystemSemantic proximity Read ↗

Aspergillus fumigatus biofilms: Toward understanding how growth as a multicellular network increases antifungal resistance and disease progressionSemantic proximity Read ↗

<i>Aspergillus fumigatus</i> transcription factor ZfpA regulates hyphal development and alters susceptibility to antifungals and neutrophil killing during infectionSemantic proximity Read ↗

Biofilm formation inCandida glabrata: What have we learnt from functional genomics approaches?Semantic proximity Read ↗

A Ssd1 homolog impacts trehalose and chitin biosynthesis and contributes to virulence in <i>Aspergillus fumigatus</i>Semantic proximity Read ↗

The Candida albicans transcription factor Cas5 couples stress responses, drug resistance and cell cycle regulation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.