Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Variations in the frequencies of polymorphisms in the CYP2C9 gene in six major ethnicities of Pakistan.

Scientific reports - 9 Nov 2020

Ahmed Sagheer, Altaf Nadeem, Ejaz Mahnoor, Altaf Aisha, Amin Aneela, Janjua Kholood, Khan Arif Ullah, Imran Imran, Khan Saeed

Abstract excerpt

Genetic variation in cytochrome P450 (CYP) 2C9 is known to cause significant inter-individual differences in drug response and adverse effects. The frequencies of CYP2C9*2 and CYP2C9*3, both of which are responsible for the low activity of the enzyme, are not known in the Pakistani population. Therefore, we screened various ethnic groups residing in Pakistan for these polymorphisms. A total of 467 healthy human...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Asian People

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP2C9

Share to Gene Frequency

Share to Pakistan

Share to Polymorphism, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 33168919
DOI: 10.1038/s41598-020-76366-x
PMCID: PMC7652876

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Variations in the frequencies of polymorphisms in the CYP2C9 gene in six major ethnicities of Pakistan.PMID 33168919Read ↗

Estimation of polymorphisms in the drug-metabolizing enzyme, cytochrome P450 2C19 gene in six major ethnicities of Pakistan.Semantic proximity Read ↗

Genetic variations in drug-metabolizing enzyme CYP2C9 among major ethnic groups of Pakistani population.Semantic proximity Read ↗

The prevalence of pharmacogenetic variants of vitamin K epoxide reductase complex subunit 1 gene (rs9923231), cytochrome P450 family 2 subfamily C member 9 gene (rs1799853) and cytochrome P450 family 3 subfamily-A member-5 gene (rs776746) among 13 ethnic groups of Pakistan.Semantic proximity Read ↗

Implications of genetic variation of common Drug Metabolizing Enzymes and ABC Transporters among the Pakistani PopulationSemantic proximity Read ↗

Allele and genotype frequencies of CYP2C9 within an Iranian population (Mazandaran).Semantic proximity Read ↗

Major Allele Frequencies in CYP2C9 and CYP2C19 in Asian and European Populations: A Case Study to Disaggregate Data Among Large Racial CategoriesSemantic proximity Read ↗

Global distribution of functionally important CYP2C9 alleles and their inferred metabolic consequences.Semantic proximity Read ↗

Pharmacogenetic relevant polymorphisms of CYP2C9, CYP2C19, CYP2D6, and CYP3A5 in Bhutanese population.Semantic proximity Read ↗

Impact of CYP2C9 genetic polymorphism on warfarin dose requirements in Pakistani population.Semantic proximity Read ↗

Distribution of the major cytochrome P450 (CYP) 2C9 genetic variants in a Saudi population.Semantic proximity Read ↗

Major Allele Frequencies in <em>CYP2C9</em> and <em>CYP2C19</em> in Asian and European Populations: A Case Study to Disaggregate Data Among Large Racial CategoriesSemantic proximity Read ↗

Allele and genotype frequency of CYP2C9 in Tamilnadu population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.