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Article

Baicalein suppresses growth of non-small cell lung carcinoma by targeting MAP4K3.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Jan 2021

Li Jian, Yan Lijun, Luo Jianghan, Tong Li, Gao Yuan, Feng Wei, Wang Fuling, Cui Wenyu, Li Siming, Sun Zhiwei

Abstract excerpt

Exploring key genes associated with non-small cell lung carcinoma (NSCLC) may lead to targeted therapies for NSCLC patients. The protein kinase MAP4K3 has been established as an important modulator of cell growth and autophagy in mammals. Herein, we investigated the somatic mutations and the expression pattern of MAP4K3 detected in NSCLC patients based on the TCGA database. Abnormal MAP4K3 expression and its...

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PMID: 33166766
DOI: 10.1016/j.biopha.2020.110965

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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