Article
The compound of baicalein, wogonin, and oroxylin-A inhibiting EMT in A549 cell line via PI3K/AKT-TWIST1- glycolysis pathway
2021-05-14
Abstract excerpt
Non-small cell lung cancer (NSCLC) is a worldwide disease with high morbidity and mortality, which is most derived from its metastasis. Some researches show that the epithelial-mesenchymal transition (EMT) process promotes lung cancer cells migration and invasion, leading to NSCLC metastasis. Total Flavonoid Aglycones Extract (TFAE) isolated from Scutellaria baicalensis was reported to inhibit tumor growth and in...
Topics
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- Bioactive Compounds and Antitumor Agents
- Cytokine Signaling Pathways and Interactions
- Heat shock proteins research
- Microbial Natural Products and Biosynthesis
- Natural product bioactivities and synthesis
- Pharmacological Effects of Natural Compounds
- Plant biochemistry and biosynthesis
- Traditional Chinese Medicine Analysis
Identifiers and source
- Literature Corpus work
- d8f2e07a-4ee6-5173-bc8a-57a83a389b75
- DOI
- 10.1101/2021.05.13.443958
