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Cutting Edge: FcR-Like 6 Is an MHC Class II Receptor

2 Jun 2010

Abstract excerpt

Receptors for the Fc portion of Ig have been extensively characterized and are known to regulate humoral responses, but members of the closely related FcR-like (FCRL) family have not been found to bind Ig, and to date, no ligand has been identified for any FCRL. Using a cell-based GFP reporter system and a recombinant Fc chimeric protein, we show that human FCRL6, a receptor selectively expressed by cytotoxic T...

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PMID: 20519654
DOI: 10.4049/jimmunol.1000832

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