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Article

FCRL6 distinguishes mature cytotoxic lymphocytes and is upregulated in patients with B‐cell chronic lymphocytic leukemia

1 Nov 2008

Abstract excerpt

Fc receptor-like 6 (FCRL6), the most recently characterized member of the FCRL family, is a cell surface glycoprotein with tyrosine-based regulatory potential. An extensive survey of human hematopoietic tissues disclosed that FCRL6 expression by NK- and T-cell subpopulations increases as a function of differentiation and is remarkably restricted to mature lymphocytes with cytotoxic capability. In particular,...

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Identifiers

PMID: 18991291
DOI: 10.1002/eji.200838516

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