Article
Associations Between Alcohol Intake and Genetic Predisposition With Atrial Fibrillation Risk in a National Biobank.
Circulation. Genomic and precision medicine - 1 Dec 2020
Halford Jennifer L, Weng Lu-Chen, Choi Seung Hoan, Jurgens Sean J, Morrill Valerie N, Khurshid Shaan, Trinquart Ludovic, Benjamin Emelia J, Ellinor Patrick T, Lubitz Steven A
Abstract excerpt
BACKGROUND: Excess alcohol intake and inherited predisposition may increase risk of atrial fibrillation (AF). We assessed the association between alcohol intake, polygenic predisposition to AF, and incident AF in the UK Biobank, a prospective cohort study. METHODS: In 376 776 UK Biobank participants enrolled between 2006 and 2010, we tested alcohol consumption (stratified by the Centers of Disease Control and...
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