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Article

Clustering of Alzheimer's and Parkinson's disease based on genetic burden of shared molecular mechanisms.

Scientific reports - 5 Nov 2020

Emon Mohammad Asif, Heinson Ashley, Wu Ping, Domingo-Fernández Daniel, Sood Meemansa, Vrooman Henri, Corvol Jean-Christophe, Scordis Phil, Hofmann-Apitius Martin, Fröhlich Holger

Abstract excerpt

One of the visions of precision medicine has been to re-define disease taxonomies based on molecular characteristics rather than on phenotypic evidence. However, achieving this goal is highly challenging, specifically in neurology. Our contribution is a machine-learning based joint molecular subtyping of Alzheimer's (AD) and Parkinson's Disease (PD), based on the genetic burden of 15 molecular mechanisms...

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Identifiers

PMID: 33154531
DOI: 10.1038/s41598-020-76200-4
PMCID: PMC7645798

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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