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Article

Molecular subtyping of Alzheimer's disease with consensus non-negative matrix factorization.

PloS one - 1 Jan 2021

Zheng Chunlei, Xu Rong

Abstract excerpt

Alzheimer's disease (AD) is a heterogeneous disease and exhibits diverse clinical presentations and disease progression. Some pathological and anatomical subtypes have been proposed. However, these subtypes provide a limited mechanistic understanding for AD. Leveraging gene expression data of 222 AD patients from The Religious Orders Study and Memory and Aging Project (ROSMAP) Study, we identified two AD...

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Identifiers

PMID: 34014928
DOI: 10.1371/journal.pone.0250278
PMCID: PMC8136734

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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