Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Plasmablasts derive from CD23– activated B cells after the extinction of IL-4/STAT6 signaling and IRF4 induction

4 Nov 2020

Abstract excerpt

The terminal differentiation of B cells into antibody-secreting cells (ASCs) is a critical component of adaptive immune responses. However, it is a very sensitive process, and dysfunctions lead to a variety of lymphoproliferative neoplasias including germinal center-derived lymphomas. To better characterize the late genomic events that drive the ASC differentiation of human primary naive B cells, we used our in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immune Cell Function and Interaction
Share to Lymphoma Diagnosis and Treatment
Share to T-cell and B-cell Immunology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33150420
DOI: 10.1182/blood.2020005083

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Plasmablasts derive from CD23– activated B cells after the extinction of IL-4/STAT6 signaling and IRF4 inductionPMID 33150420Read ↗

Integrated single cell multiomic profiling and functional validation reveal distinct cellular routes to human plasma cell differentiationSemantic proximity Read ↗

Three-Dimensional Epigenome Roadmap of Human B-cell Differentiation Uncovers Mechanisms of Humoral Immunity and OncogenesisSemantic proximity Read ↗

High-resolution single-cell atlas of the human B cell compartment and immune microenvironment across tissuesSemantic proximity Read ↗

Unraveling B cell trajectories at single cell resolutionSemantic proximity Read ↗

Integrative single-cell chromatin and transcriptome analysis of human plasma cell differentiationSemantic proximity Read ↗

Single-cell analysis reveals dynamics of human B cell differentiation and identifies novel B and antibody-secreting cell intermediatesSemantic proximity Read ↗

Human Bone Marrow Plasma Cell Atlas: Maturation and Survival Pathways Unraveled by Single Cell AnalysesSemantic proximity Read ↗

Single‐cell resolution of plasma cell fate programming in health and diseaseSemantic proximity Read ↗

An in vitro model of differentiation of memory B cells into plasmablasts and plasma cells including detailed phenotypic and molecular characterizationSemantic proximity Read ↗

Plasma cells in immunopathology: concepts and therapeutic strategies.Semantic proximity Read ↗

Single-cell analysis of germinal-center B cells informs on lymphoma cell of origin and outcomeSemantic proximity Read ↗

Single-cell analysis reveals multi-faceted features of B cell development together with age-associated B cell subpopulationsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.