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Tumor mutation burden in connection with immune-related survival in uterine corpus endometrial carcinoma

28 Jan 2021

Abstract excerpt

BACKGROUND: UCEC is the most common gynecological malignancy in many countries, and its mechanism of occurrence and development is related to tumor mutation burden (TMB) and immune cell infiltration. Therefore, it is necessary to systematically explore the TMB-related gene profile in immune cells to improve the prognosis of UCEC. METHODS: We integrated TMB-related genes with basic clinical information of UCEC...

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PMID: 33509222
DOI: 10.1186/s12935-021-01774-6

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