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Integrated analysis of tumor mutation burden and immune infiltrates in endometrial cancer.

Current problems in cancer - 1 Apr 2021

Zhou Hongyu, Chen Lihua, Lei Yajie, Li Tianjiao, Li Haoran, Cheng Xi

Abstract excerpt

To explore the prognostic value of tumor mutation burden (TMB) and its correlation with immune infiltrates in endometrial cancer. Transcriptome and somatic mutation profiles of Uterine Corpus Endometrial Carcinoma (UCEC) were downloaded from TCGA database. Somatic mutations were analyzed by "maftools" and visualized in waterfall plot. We calculated TMB of each patients and divided all patients into the high-TMB...

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Identifiers

PMID: 33012523
DOI: 10.1016/j.currproblcancer.2020.100660

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