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The role of nicotinic receptors in SARS-CoV-2 receptor ACE2 expression in intestinal epithelia

27 Oct 2020

Abstract excerpt

Abstract Background Recent evidence demonstrated that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) propagates in intestinal epithelial cells expressing Angiotensin-Converting Enzyme 2 (ACE2), implying that these cells represent an important entry site for the viral infection. Nicotinic receptors (nAChRs) have been put forward as potential regulators of inflammation and of ACE2 expression. As vagus...

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PMID: 33123616
DOI: 10.1186/s42234-020-00057-1

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