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Single cell RNA sequencing of 13 human tissues identify cell types and receptors of human coronaviruses

18 Mar 2020

Abstract excerpt

The new coronavirus (SARS-CoV-2) outbreak from December 2019 in Wuhan, Hubei, China, has been declared a global public health emergency. Angiotensin I converting enzyme 2 (ACE2), is the host receptor by SARS-CoV-2 to infect human cells. Although ACE2 is reported to be expressed in lung, liver, stomach, ileum, kidney and colon, its expressing levels are rather low, especially in the lung. SARS-CoV-2 may use...

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PMID: 32199615
DOI: 10.1016/j.bbrc.2020.03.044

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