Article

SARS-CoV-2 Receptor ACE2 Gene Expression in Small Intestine correlates with Age

2020-05-21

Abstract excerpt

<title>Abstract</title> <p>SARS-CoV-2 binds via its spikes to its receptor angiotensin-converting enzyme 2 (ACE2). ACE2 is also expressed in small intestinal enterocytes, making the intestine a possible entry site. We examined duodenal biopsies from 43 healthy human adults. ACE2 gene expression was directly correlated with age (Spearman’s r= 0.317, p=0.039. With each year duodenal ACE2 expression increased by 0.0...

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Literature Corpus work: 318d19c1-8cbe-55df-bdc5-1f290d7dd0e8
DOI: 10.21203/rs.3.rs-30376/v1

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