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Article

Molecular mechanism for the interaction between human CPSF30 and hFip1.

Genes & development - 1 Dec 2020

Hamilton Keith, Tong Liang

Abstract excerpt

Most eukaryotic pre-mRNAs must undergo 3'-end cleavage and polyadenylation prior to their export from the nucleus. A large number of proteins in several complexes participate in this 3'-end processing, including cleavage and polyadenylation specificity factor (CPSF) in mammals. The CPSF30 subunit contains five CCCH zinc fingers (ZFs), with ZF2-ZF3 being required for the recognition of the AAUAAA poly(A) signal....

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Identifiers

PMID: 33122294
DOI: 10.1101/gad.343814.120
PMCID: PMC7706699

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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