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Article

Macrophage inhibitory cytokine-1 in cancer: Beyond the cellular phenotype.

Cancer letters - 28 Jun 2022

Muniyan Sakthivel, Pothuraju Ramesh, Seshacharyulu Parthasarathy, Batra Surinder K

Abstract excerpt

Despite technological advances in diagnostic abilities and improved treatment methods, the burden of cancers remains high, leading to significant morbidity and mortality. One primary reason is that cancer cell secretory factors modulate the tumor microenvironment, supporting tumor growth and circumvents anticancer activities of conventional therapies. Macrophage inhibitory cytokine-1 (MIC-1) is a pleiotropic...

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Identifiers

PMID: 35351601
DOI: 10.1016/j.canlet.2022.215664
PMCID: PMC9088220

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