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Article

Mohawk is a transcription factor that promotes meniscus cell phenotype and tissue repair and reduces osteoarthritis severity.

Science translational medicine - 28 Oct 2020

Lee Kwang Il, Gamini Ramya, Olmer Merissa, Ikuta Yasunari, Hasei Joe, Baek Jihye, Alvarez-Garcia Oscar, Grogan Shawn P, D'Lima Darryl D, Asahara Hiroshi, Su Andrew I, Lotz Martin K

Abstract excerpt

Meniscus tears are common knee injuries and a major osteoarthritis (OA) risk factor. Knowledge gaps that limit the development of therapies for meniscus injury and degeneration concern transcription factors that control the meniscus cell phenotype. Analysis of RNA sequencing data from 37 human tissues in the Genotype-Tissue Expression database and RNA sequencing data from meniscus and articular cartilage showed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33115953
DOI: 10.1126/scitranslmed.aan7967
PMCID: PMC7955769

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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