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Article

Gene expression profiles of the meniscus avascular phenotype: A guide for meniscus tissue engineering.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 Jul 2018

Grogan Shawn P, Duffy Stuart F, Pauli Chantal, Lotz Martin K, D'Lima Darryl D

Abstract excerpt

Avascular (Avas) meniscus regeneration remains a challenge, which is partly a consequence of our limited knowledge of the cells that maintain this tissue region. In this study, we utilized microarrays to characterize gene expression profiles of intact human Avas meniscus tissue and of cells following culture expansion. Using these data, we examined various 3D culture conditions to redifferentiate Avas cells...

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Identifiers

PMID: 29411909
DOI: 10.1002/jor.23864
PMCID: PMC6326361

Genes

BMP6
THBS2
THBS4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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