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Differentiation of ciliated human midbrain-derived LUHMES neurons

28 Oct 2020

Abstract excerpt

ABSTRACT Many human cell types are ciliated, including neural progenitors and differentiated neurons. Ciliopathies are characterized by defective cilia and comprise various disease states, including brain phenotypes, where the underlying biological pathways are largely unknown. Our understanding of neuronal cilia is rudimentary, and an easy-to-maintain, ciliated human neuronal cell model is absent. The Lund human...

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PMID: 33115758
DOI: 10.1242/jcs.249789

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