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Article

Complement as a Biological Tool to Control Tumor Growth

25 Sept 2018

Abstract excerpt

studies have revealed a double role played by this system in tumor progression. Complement activation in the cancer microenvironment has been shown to promote cancer growth through the release of the chemotactic peptide C5a recruiting myeloid suppressor cells. There is also evidence that tumor progression can be controlled by complement activated on the surface of cancer cells through one of the three pathways of...

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PMID: 30319647
DOI: 10.3389/fimmu.2018.02203

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