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Cell-Type Specific Profiling of Histone Post-Translational Modifications in the Adult Mouse Striatum

2022-01-20

Abstract excerpt

Histone post-translational modifications (hPTMs) regulate gene expression via changes in chromatin accessibility and transcription factor recruitment. At a given locus, the coordinated enrichment of several distinct hPTMs regulate gene expression in response to external stimuli. However, neuronal hPTMs have been primarily characterized in bulk brain tissue and/or tissue pooled across subjects. This obscures both c...

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Literature Corpus work
6522abb2-bcc2-5819-9bbe-4834fb924020
DOI
10.1101/2022.01.17.476614
Open publication

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Cell-Type Specific Profiling of Histone Post-Translational Modifications in the Adult Mouse StriatumDOI 10.1101/2022.01.17.476614
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