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Article

Effects of the MTOR and AKT1 genes polymorphisms on papillary thyroid cancer development.

IUBMB life - 1 Dec 2020

Maruei-Milan Rostam, Saravani Mohsen, Heidari Zahra, Asadi-Tarani Mina, Salimi Saeedeh

Abstract excerpt

Papillary thyroid cancer (PTC) is the most common form of thyroid cancer, comprising 80% of all thyroid malignancies. The phosphoinositide-3-kinase-protein kinase B/Akt (PI3K-PKB/Akt) pathway is a main pathway in control of cell growth. Activated mTOR and Akt are involved in the development and progression of the PTC. This study aimed to evaluate the effects of MTOR (rs2536 and rs2295080) and AKT1 (rs2494732,...

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Source

Identifiers

PMID: 33107190
DOI: 10.1002/iub.2388

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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