Article
Genetic Variants Associated with Non-Alcoholic Fatty Liver Disease Do Not Associate with Measures of Sub-Clinical Atherosclerosis: Results from the IMPROVE Study.
Genes - 22 Oct 2020
Castaldo Luigi, Laguzzi Federica, Strawbridge Rona J, Baldassarre Damiano, Veglia Fabrizio, Vigo Lorenzo, Tremoli Elena, de Faire Ulf, Eriksson Per, Smit Andries J, Aubrecht Jiri, Leander Karin, Pirro Matteo, Giral Philippe, Ritieni Alberto, Di Minno Giovanni, Mälarstig Anders, Gigante Bruna
Abstract excerpt
Non-alcoholic fatty liver disease (NAFLD) and atherosclerosis-related cardiovascular diseases (CVD) share common metabolic pathways. We explored the association between three NAFLD-associated single nucleotide polymorphisms (SNPs) rs738409, rs10401969, and rs1260326 with sub-clinical atherosclerosis estimated by the carotid intima-media thickness (c-IMT) and the inter-adventitia common carotid artery diameter...
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