Article

Striatal volume and functional connectivity predict weight gain in early-phase psychosis

2018-12-19

Abstract excerpt

<h4>Background: </h4> Second-generation antipsychotic drugs (SGAs) are essential in the treatment of psychotic disorders, but are well-known for inducing substantial weight gain and obesity. Critically, weight gain may reduce life expectancy for up to 20-30 years in patients with psychotic disorders, and prognostic biomarkers are generally lacking. The dorsal striatum, rich in dopamine D2 receptors which are antag...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 14d30a88-b611-52f0-ac10-a7dc61f849e0
DOI: 10.1101/501825

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Striatal volume and functional connectivity predict weight gain in early-phase psychosisDOI 10.1101/501825Read

Associations between antipsychotics-induced weight gain and brain networks of impulsivitySemantic proximity Read

BMIgap: a new tool to quantify transdiagnostic brain signatures of current and future weightSemantic proximity Read

Higher BMI, but not obesity-related genetic polymorphisms, correlates with lower structural connectivity of the reward network in a population-based study.Semantic proximity Read

Reproducible Human Reward Imaging Phenotypes Exhibit Differential Sensitivity to Dopamine D2 Receptor AntagonismSemantic proximity Read

Orbitofrontal-striatal structural alterations linked to negative symptoms at different stages of the schizophrenia spectrumSemantic proximity Read

Neuroanatomical substrates in Parkinson’s Disease psychosis and their association with serotonergic receptor gene expression: A coordinate-based meta-regression analysisSemantic proximity Read

An overview of the central control of weight regulation and the effect of antipsychotic medication.Semantic proximity Read

Postprint: Medial temporal lobe and basal ganglia volume trajectories in persistent negative symptoms following a first episode of psychosisSemantic proximity Read

Network and receptor architectures shape brain morphometry in addictionSemantic proximity Read

Striatal functional connectivity in psychosis relapse: A comparison between antipsychotic adherent and non-adherent patients at the time of relapseSemantic proximity Read

Polygenic Risk of Psychosis and Ventral Striatal Activation During Reward Processing in Healthy Adolescents.Semantic proximity Read

Does Sex affect Antipsychotic Associated Weight Gain in Patients Being Treated for Psychotic Disorders: A Protocol for a Systematic ReviewSemantic proximity Read