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Article

Novel genetic variants associated with brain functional networks in 18,445 adults from the UK Biobank.

Scientific reports - 16 Jul 2021

Foo Heidi, Thalamuthu Anbupalam, Jiang Jiyang, Koch Forrest C, Mather Karen A, Wen Wei, Sachdev Perminder S

Abstract excerpt

Here, we investigated the genetics of weighted functional brain network graph theory measures from 18,445 participants of the UK Biobank (44-80 years). The eighteen measures studied showed low heritability (mean h2SNP = 0.12) and were highly genetically correlated. One genome-wide significant locus was associated with strength of somatomotor and limbic networks. These intergenic variants were located near the...

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Identifiers

PMID: 34272439
DOI: 10.1038/s41598-021-94182-9
PMCID: PMC8285376

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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