Article
Body mass index but not genetic risk is longitudinally associated with altered structural brain parameters.
Scientific reports - 20 Dec 2021
Tüngler Anne, Van der Auwera Sandra, Wittfeld Katharina, Frenzel Stefan, Terock Jan, Röder Nele, Homuth Georg, Völzke Henry, Bülow Robin, Grabe Hans Jörgen, Janowitz Deborah
Abstract excerpt
Evidence from previous studies suggests that elevated body mass index (BMI) and genetic risk for obesity is associated with reduced brain volume, particularly in areas of reward-related cognition, e.g. the medial prefrontal cortex (AC-MPFC), the orbitofrontal cortex (OFC), the striatum and the thalamus. However, only few studies examined the interplay between these factors in a joint approach. Moreover, previous...
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