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Article

Generalized, focal, and combined epilepsies in families: New evidence for distinct genetic factors.

Epilepsia - 1 Dec 2020

Ellis Colin A, Ottman Ruth, Epstein Michael P, Berkovic Samuel F

Abstract excerpt

OBJECTIVE: To determine the roles of shared and distinct genetic influences on generalized and focal epilepsy operating in individuals who manifest features of both types (combined epilepsies), and in families manifesting both generalized and focal epilepsies in separate individuals (mixed families). METHODS: We analyzed the deeply phenotyped Epi4K cohort of multiplex families (≥3 affected individuals per family)...

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Identifiers

PMID: 33098311
DOI: 10.1111/epi.16732
PMCID: PMC7725856

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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