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Article

Immunization against αIIb β3 and αv β3 in Glanzmann thrombasthenia patients carrying the French Gypsy mutation.

Journal of thrombosis and haemostasis : JTH - 1 Jan 2021

Fiore Mathieu, Bayat Behnaz, Phuangtham Roongaroon, Blouin Laura, Huguenin Yoann, Bein Gregor, Santoso Sentot

Abstract excerpt

Essentials The c.1544+1G>A mutation was identified in Gypsy Glanzmann thrombasthenia (GT) patients. Gypsy GT patients express normal αv β3 carrying HPA-1b epitopes. To demonstrate HPA-1a alloimmunization by modified antigen capture assays. Gypsy GT patients could develop anti-HPA-1a alloantibodies against β3 and αv β3 . ABSTRACT: Background Glanzmann thrombasthenia (GT) is a rare bleeding disorder caused by the...

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Identifiers

PMID: 33090654
DOI: 10.1111/jth.15117

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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