Genotyping provides a reliable tool for the determination of the platelet antigen system HPA-1 in Glanzmann's thrombasthenia.

doi:10.1111/j.1365-2141.1993.tb08653.x

Back to search

Article

Genotyping provides a reliable tool for the determination of the platelet antigen system HPA-1 in Glanzmann's thrombasthenia.

British journal of haematology - 1 Sept 1993

Pober M, Kyrle P A, Panzer S

Abstract excerpt

Glanzmann's thrombasthenia (GT) is an inherited disorder of platelet function, characterized by quantitative or qualitative defects of the platelet glycoprotein (GP) IIb/IIIa complex. Patients with GT may require repeated transfusions and therefore alloimmunization against platelet antigens could...

Topics

Antigens, Human Platelet
Base Sequence
Blood Platelets
DNA
Genotype
Humans
Molecular Sequence Data
Polymerase Chain Reaction
Thrombasthenia

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.