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Article

Developmental Adaptive Immune Defects Associated with STAT5B Deficiency in Three Young Siblings.

Journal of clinical immunology - 1 Jan 2021

Foley Corinne L, Al Remeithi Sareea S, Towe Christopher T, Dauber Andrew, Backeljauw Philippe F, Tyzinski Leah, Kumar Ashish R, Hwa Vivian

Abstract excerpt

Patients with rare homozygous mutations in signal transducer and activator of transcription 5B (STAT5B) develop immunodeficiency resulting in chronic eczema, chronic infections, autoimmunity, and chronic lung disease. STAT5B-deficient patients are typically diagnosed in the teenage years, limiting our understanding of the development of associated phenotypic immune abnormalities. We report the first detailed...

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Source

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Identifiers

PMID: 33090292
DOI: 10.1007/s10875-020-00884-6
PMCID: PMC7854992

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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