Article
Role of the inositol polyphosphate kinase Vip1 in autophagy and pathogenesis in Candida albicans.
Future microbiology - 1 Sept 2020
Ma Tianyu, Yu Qilin, Ma Congcong, Mao Xiaolong, Liu Yingzheng, Peng Xueling, Li Mingchun
Abstract excerpt
Aim: Inositol polyphosphate kinases are involved in regulation of many cellular processes in eukaryotic cells. In this study, we investigated the functions of the inositol polyphosphate kinase Vip1 in autophagy and pathogenicity of Candida albicans. Results: Loss of Vip1 caused significantly increased sensitivity to nitrogen source starvation, abnormal localization and degradation of autophagy protein, higher...
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