Article
Evaluating the precision of EBF1 SNP x stress interaction association: sex, race, and age differences in a big harmonized data set of 28,026 participants.
Translational psychiatry - 20 Oct 2020
Singh Abanish, Babyak Michael A, Sims Mario, Musani Solomon K, Brummett Beverly H, Jiang Rong, Kraus William E, Shah Svati H, Siegler Ilene C, Hauser Elizabeth R, Williams Redford B
Abstract excerpt
In prior work, we identified a novel gene-by-stress association of EBF1's common variation (SNP rs4704963) with obesity (i.e., hip, waist) in Whites, which was further strengthened through multiple replications using our synthetic stress measure. We now extend this prior work in a precision medicine framework to find the risk group using harmonized data from 28,026 participants by evaluating the following: (a)...
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