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Article

Gene by stress genome-wide interaction analysis and path analysis identify EBF1 as a cardiovascular and metabolic risk gene.

European journal of human genetics : EJHG - 1 Jun 2015

Singh Abanish, Babyak Michael A, Nolan Daniel K, Brummett Beverly H, Jiang Rong, Siegler Ilene C, Kraus William E, Shah Svati H, Williams Redford B, Hauser Elizabeth R

Abstract excerpt

We performed gene-environment interaction genome-wide association analysis (G × E GWAS) to identify SNPs whose effects on metabolic traits are modified by chronic psychosocial stress in the Multi-Ethnic Study of Atherosclerosis (MESA). In Whites, the G × E GWAS for hip circumference identified five SNPs within the Early B-cell Factor 1 (EBF1) gene, all of which were in strong linkage disequilibrium. The...

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Source

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Identifiers

PMID: 25271088
DOI: 10.1038/ejhg.2014.189
PMCID: PMC4795045

Genes

EBF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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