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Article

Oncogenic and Tumor-Suppressive Functions of NOTCH Signaling in Glioma

15 Oct 2020

Abstract excerpt

Although the role of NOTCH signaling has been extensively studied in health and disease, many questions still remain unresolved. Being crucial for tissue homeostasis, NOTCH signaling is also implicated in multiple cancers by either promoting or suppressing tumor development. In this review we illustrate the context-dependent role of NOTCH signaling during tumorigenesis with a particular focus on gliomas, the most...

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PMID: 33076453
DOI: 10.3390/cells9102304

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