Non-coding RNAs as Key Regulators of the Notch Signaling Pathway in Glioblastoma: Diagnostic, Prognostic, and Therapeutic Targets

Abstract excerpt

Glioblastoma multiforme (GBM) is a highly invasive brain malignancy originating from astrocytes, accounting for approximately 30% of central nervous system malignancies. Despite advancements in therapeutic strategies including surgery, chemotherapy, and radiopharmaceutical drugs, the prognosis for GBM patients remains dismal. The aggressive nature of GBM necessitates the identification of molecular targets and the...

Topics

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• Cell Transformation, Neoplastic
• Gene Expression Regulation, Neoplastic
• Genetic Therapy
• Glioma
• Molecular Targeted Therapy
• RNA, Long Noncoding
• RNA Transport
• Structure-Activity Relationship

Identifiers and source

Literature Corpus work

07ef1257-8677-562e-92cb-b1c8e0e0907b

DOI

10.20944/preprints202307.1595.v1