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Article

Autophagy induction on impaired spermatogenesis of xeroderma pigmentosum group A gene-deficient mice.

Biomedical research (Tokyo, Japan) - 1 Jan 2020

Nakane Hironobu, Higaki Katsumi, Koyama Yuka, Nanba Eiji, Kaidoh Toshiyuki

Abstract excerpt

Xeroderma pigmentosum (XP) involves a defect in the initial step of nucleotide excision repair (NER) and consists of eight genetic complementation groups (groups A-G and a variant). XP group A (XPA) patients have a high incidence of UV-induced skin tumors, immature testicular development, and neurological symptoms. In an earlier study, we have shown that XP group A (Xpa) gene-knockout mice (Xpa-/- mice) were...

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Identifiers

PMID: 33071259
DOI: 10.2220/biomedres.41.237

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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