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Contribution of long-chain fatty acid to induction of myeloid-derived suppressor cell (MDSC)-like cells - induction of MDSC by lipid vesicles (liposome).

Immunopharmacology and immunotoxicology - 1 Dec 2020

Yoshida Yoichiro, Nagamori Tsunehisa, Ishibazawa Emi, Kobayashi Hiroya, Kure Tomoko, Sakai Hiromi, Takahashi Daisuke, Fujihara Mitsuhiro, Azuma Hiroshi

Abstract excerpt

CONTEXT: Effects of liposomal particles on immune function have not been adequately investigated. Earlier reports indicate that intravenous injection of rats with pegylated liposomes comprising chemically defined specific lipids produces myeloid derived suppressor-cell (MDSC)-like cells in the spleen. OBJECTIVES: After liposome injection, we sought a cell surface marker expressed specifically on splenic...

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Identifiers

PMID: 33070657
DOI: 10.1080/08923973.2020.1837866

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