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Article

Adipokines Regulate the Expression of Tumor-Relevant MicroRNAs

1 Jan 2019

Abstract excerpt

BACKGROUND: Increasing prevalence of obesity requires the investigation of respective comorbidities, including tumor diseases like colorectal, renal, post-menopausal breast, prostate cancer, and leukemia. To date, molecular mechanisms of the malignant transformation of these peripheral tissues induced by obesity remain unclear. Adipose tissue secretes factors with hormone-like functions, the adipokines, and is...

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PMID: 30999294
DOI: 10.1159/000496625

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