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Article

Tumor-associated macrophages in skin: How to treat their heterogeneity and plasticity.

Journal of dermatological science - 1 Sept 2016

Fujimura Taku, Kakizaki Aya, Furudate Sadanori, Kambayashi Yumi, Aiba Setsuya

Abstract excerpt

Immunosuppressive tumor-associated macrophages (TAMs) promote an immunosuppressive environment in the tumor-bearing host, together with regulatory T cells (Tregs). TAMs compose cancer stroma in skin cancers including melanomas and non-melanomas. The majority of tumor-associated macrophages (TAMs) are alternatively activated M2 macrophages that favor tumor development, and they comprise one of the main populations...

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Source

Identifiers

PMID: 27291068
DOI: 10.1016/j.jdermsci.2016.05.015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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