Article
Genetic Loci and Physiologic Pathways Involved in Gestational Diabetes Mellitus Implicated Through Clustering.
Diabetes - 1 Jan 2021
Powe Camille E, Udler Miriam S, Hsu Sarah, Allard Catherine, Kuang Alan, Manning Alisa K, Perron Patrice, Bouchard Luigi, Lowe William L, Scholtens Denise, Florez Jose C, Hivert Marie-France
Abstract excerpt
Hundreds of common genetic variants acting through distinguishable physiologic pathways influence the risk of type 2 diabetes (T2D). It is unknown to what extent the physiology underlying gestational diabetes mellitus (GDM) is distinct from that underlying T2D. In this study of >5,000 pregnant women from three cohorts, we aimed to identify physiologically related groups of maternal variants associated with GDM...
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