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Distinct and shared genetic architectures of gestational diabetes mellitus and type 2 diabetes

5 Jan 2024

Abstract excerpt

Abstract Gestational diabetes mellitus (GDM) is a common metabolic disorder affecting more than 16 million pregnancies annually worldwide 1,2 . GDM is related to an increased lifetime risk of type 2 diabetes (T2D) 1–3 , with over a third of women developing T2D within 15 years of their GDM diagnosis. The diseases are hypothesized to share a genetic predisposition 1–7 , but few studies have sought to uncover the...

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PMID: 38182742
DOI: 10.1038/s41588-023-01607-4

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