Article
Prevalence of mismatch repair deficiency and Lynch syndrome in a cohort of unselected small bowel adenocarcinomas.
Journal of clinical pathology - 1 Nov 2021
Suerink Manon, Kilinç Gül, Terlouw Diantha, Hristova Hristina, Sensuk Lily, van Egmond Demi, Farina Sarasqueta Arantza, Langers Alexandra M J, van Wezel Tom, Morreau Hans, Nielsen Maartje
Abstract excerpt
AIMS: Previous estimates of the prevalence of mismatch repair (MMR) deficiency and Lynch syndrome in small bowel cancer have varied widely. The aim of this study was to establish the prevalence of MMR deficiency and Lynch syndrome in a large group of small bowel adenocarcinomas. METHODS: To this end, a total of 400 small bowel adenocarcinomas (332 resections, 68 biopsies) were collected through the Dutch...
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