Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Royal jelly attenuates metabolic defects in a Drosophila mutant with elevated TORC1 activity.

Biology open - 6 Nov 2020

Cheng Yang, Cai Jiadong, Fu Yuanyuan, Feng Congjing, Hao Yue, Wei Youheng

Abstract excerpt

Target of rapamycin complex 1 (TORC1) is a master regulator of cell metabolism, and its dysregulation has been linked to an array of pathologies, including cancer and age-related diseases. Nprl3, a component of GTPase-activating protein towards Rags complex 1 (GATOR1), inhibits TORC1 activity under nutrient scarcity status. The nprl3 mutant exhibits some metabolic defects due to hyper TORC1 activity in Drosophila...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Genetically Modified
Share to Antioxidants
Share to Drosophila

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Energy Metabolism

Share to Fatty Acids

Share to Mechanistic Target of Rapamycin Complex 1

Share to Oxidoreductases

Share to Reactive Oxygen Species

Source

Open in PubMed Open full text

Identifiers

PMID: 33037015
DOI: 10.1242/bio.054999
PMCID: PMC7657477

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Royal jelly attenuates metabolic defects in a Drosophila mutant with elevated TORC1 activity.PMID 33037015Read ↗

Drosophila as a toolkit to tackle cancer and its metabolismSemantic proximity Read ↗

Extension of Drosophila Lifespan by Rhodiola rosea through a Mechanism Independent from Dietary RestrictionSemantic proximity Read ↗

Using Drosophila melanogaster to Dissect the Roles of the mTOR Signaling Pathway in Cell GrowthSemantic proximity Read ↗

Target of Rapamycin (TOR) Regulates Growth in Response to Nutritional SignalsSemantic proximity Read ↗

Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans.Semantic proximity Read ↗

Structure-based engineering of Tor complexes uncovers different roles of two types of yeast TORC1sSemantic proximity Read ↗

Dietary fiber supplementation increases Drosophila melanogaster lifespan and gut microbiota diversitySemantic proximity Read ↗

MAP4K3 regulates body size and metabolism in Drosophila.Semantic proximity Read ↗

Dysfunctional peroxisomes compromise gut structure and host defense by increased cell death and Tor-dependent autophagySemantic proximity Read ↗

Molecular mechanisms of exceptional lifespan increase of Drosophila melanogaster with different genotypes after combinations of pro-longevity interventions.Semantic proximity Read ↗

Acarbose suppresses symptoms of mitochondrial disease in a mouse model of Leigh SyndromeSemantic proximity Read ↗

Rapamycin enhances survival in a Drosophila model of mitochondrial disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.