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Article

BsmI-ApaI-TaqI TAC (BAt) Haplotype of Vitamin D Receptor Gene Is Associated with Increased Risk of Major Depressive Disorder.

Journal of molecular neuroscience : MN - 1 May 2021

Lye Munn-Sann, Tor Yin-Sim, Tey Yin-Yee, Shahabudin Aishah, Loh Su-Peng, Ibrahim Normala, Stanslas Johnson, Rosli Rozita, Ling King-Hwa

Abstract excerpt

Heritability of major depressive disorder (MDD) is between 36 and 44%, suggesting that up to nearly half of the phenotypic variability is attributable to genes. A number of genetic polymorphisms have been shown to predispose certain individuals to depression. Of particular interest are the polymorphisms of the vitamin D receptor (VDR) gene. Although the VDR gene has been well characterized and a vast number of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33034825
DOI: 10.1007/s12031-020-01719-0

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