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Article

PGC-1α in Disease: Recent Renal Insights into a Versatile Metabolic Regulator

3 Oct 2020

Abstract excerpt

Peroxisome proliferator-activated receptor gamma co-activator 1 alpha (PGC-1α) is perhaps best known as a master regulator of mitochondrial biogenesis and function. However, by virtue of its interactions as a coactivator for numerous nuclear receptors and transcription factors, PGC-1α also regulates many tissue-specific tasks that include adipogenesis, angiogenesis, gluconeogenesis, heme biosynthesis,...

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PMID: 33022986
DOI: 10.3390/cells9102234

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