Article
C1QTNF4 gene p.His198Gln mutation is correlated with early-onset systemic lupus erythematosus in Iranian patients.
International journal of rheumatic diseases - 1 Nov 2020
Pakzad Bahram, Shirpour Reza, Mousavi Maryam, Karimzadeh Hadi, Salehi Amirhossein, Kazemi Mehdi, Amini Guilda, Akbari Mojtaba, Salehi Rasoul
Abstract excerpt
BACKGROUND: Systemic lupus erythematosus (SLE) is an autoimmune disease with multifactorial etiology. Several studies show that genetic factors have an important part in the incidence of SLE. The C1QTNF4 gene is involved in the regulation of the inflammatory pathways by pro-inflammatory function. In the present study, we have evaluated the association between C1QTNF4 gene p.His198Gln mutation and risk of SLE....
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