Article
Nutrient consumption-dependent association of a glucagon-like peptide-1 receptor gene polymorphism with insulin secretion.
Scientific reports - 2 Oct 2020
Nishiya Yuki, Daimon Makoto, Mizushiri Satoru, Murakami Hiroshi, Tanabe Jutaro, Matsuhashi Yuki, Yanagimachi Miyuki, Tokuda Itoyo, Sawada Kaori, Ihara Kazushige
Abstract excerpt
Since type 2 diabetes (DM) is a life-style related disease, life-style should be considered when association between genetic factors and DM are examined. However, most studies did not examine genetic associations in consideration with lifestyle. Glucagon-like peptide-1 (GLP-1) receptor (GLP1R) mediates the insulinotropic action of GLP-1 in β-cells. We here examined the association while taking into consideration...
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