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Article

Genome-wide contribution of genotype by environment interaction to variation of diabetes-related traits.

PloS one - 1 Jan 2013

Zheng Ju-Sheng, Arnett Donna K, Lee Yu-Chi, Shen Jian, Parnell Laurence D, Smith Caren E, Richardson Kris, Li Duo, Borecki Ingrid B, Ordovás José M, Lai Chao-Qiang

Abstract excerpt

While genome-wide association studies (GWAS) and candidate gene approaches have identified many genetic variants that contribute to disease risk as main effects, the impact of genotype by environment (GxE) interactions remains rather under-surveyed. To explore the importance of GxE interactions for diabetes-related traits, a tool for Genome-wide Complex Trait Analysis (GCTA) was used to examine GxE variance...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24204828
DOI: 10.1371/journal.pone.0077442
PMCID: PMC3810463

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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